| Test | : | Random Urine Creatinine |
| Other Test Request Name | : | • Random Urine Crea • Spot Urine Creatinine • Spot Urine Crea • Urine Crea • Urine Creatinine |
| Test Composition | : | Not applicable |
| Intended Use | : | • Used to help evaluate the efficiency of kidney filtration. |
| Methodology | : | Enzymatic |
| Laboratory Section | : | Chemistry |
| Special Instructions/Patient Preparations | : | 1. Refrain from eating a high meat diet and doing strenuous physical activity 8-12 hours before sample collection. 2. Refrain from taking medicines such as Acetaminophen (Paracetamol), N-acetyl-p-benzoquinone imine (NAPQI) metabolites, N-Acteylcysteine (NAC), Metamizole (Novaminsulfone, Dipyrone), 4-aminoantipyrine (4-AAP) and 4-Methylamino-antipyrine (4-MAP) metabolites 8-12 hrs before sample collection. Note: If recommended preparation is not followed, you may accept but NOTE in clinical info. |
| Collection/Sample Container | : | Clean plastic container |
Specimen and Volume Requirement Note:Follow tube manufacturer recommendation. | : | 10-60 mL Random Urine |
| Alternative Specimen and Volume Requirement | : | Not applicable |
| Specimen Stability | | |
| • Room Temperature (15-25°C) | : | 2 Days |
| • Refrigerated Temperature (2-8°C) | : | 6 Days |
| • Freezer Temperature (-20°C) | : | 6 Months |
| Transport Temperature | : | Transport specimen at 2 – 8 °C (with cold packs) |
| Rejection Criteria | : | • Exceeded sample stability requirement • Quantity not sufficient • Improperly labeled specimens • Improper urine collection |
| Running Day | : | DAILY |
| Cut Off Time | : | Monday to Saturday: 6:00 PM |
| TAT/Releasing of Results | : | ROUTINE • 4 hours after receipt of specimen/ arrival of messenger STAT • After 2½ hours from extraction/messenger arrival |
| Reference Interval/Result Interpretation | : | MALE: 3.54-24.60 mmol/L (40.00-277.98 mg/dL) FEMALE: 2.55-20.00 mmol/L (28.82-226.00 mg/dL) |
| Limitations/Interferences | : | • Calcium dobesilate (e.g. Dexium), Levodopa and alpha?methyldopa cause artificially low creatinine results. Dicynone (Etamsylate) at therapeutic concentrations may lead to falsely low results. • High homogentisic acid concentrations in urine samples lead to false results. • Acetaminophen, Acetylcysteine and Metamizole are metabolized quickly. Therefore, interference from these substances is unlikely but cannot be excluded. |
| Frequently Asked Questions (FAQs) | : | Not applicable |
| Related Words/Test | : | Kidney Function, Urinalysis, Albumin, Urine Albumin, Protein Electrophoresis, Total Protein, BUN, Creatinine, eGFR |